Stylecraze has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical associations. Based on clinical trial data, a safe dosage is 420 milligrams per day of oral milk thistle containing 70 to 80 percent silymarin in divided doses for up to 41 months. Liver swelling, liver congestion, Cholecystitis or gall bladder infection, gall colic. How this happens is yet to be studied. Milk thistle might interact with statin drugs, which are known to lower cholesterol levels (lipid-lowering) (9). The fluff is not used. Partly because of this triglycdride levels are lowered. This increases the regenerative capacity (self-healing capacity) of the liver. In a review examining its effect on alcoholic liver disease, four studies found improvements in markers of healthy liver function including levels of aminotransferases, enzymes that are released into the blood when the liver is damaged. Others may include headaches, mild diarrhea, joint pain, skin allergies, rash, loss of appetite, nasal congestion and insomnia . Milk Thistle is a popular herbal remedy that may be beneficial for those who overindulge in alcohol. Yes, you can drink alcohol while taking milk thistle. Interactions between Herbs and Conventional Drugs: Overview of the Clinical Data, Karger Journals. StyleCraze believes in credibility and giving our readers access to authentic and evidence-based content. Some such drugs may include (12): Since milk thistle affects how well the liver breaks down these medications, it can affect how well these medications can work. Milk Thistle Side Effects & Precautions Side Effects Chronic alcoholic hepatitis, Liver fatty, From the 16th century onwards, the liver-protecting effect of milk thistle was seen as its most important property. Review information on amounts of silymarin found in popular brands, evidence for liver protection, diabetes and other uses. Because of these medicinal properties, phytotherapists can prescribe milk thistle: The portal circulation is the blood circulation from the intestines to the liver. Reading and theater are his other interests. It also contains the sterols cholesterol, campesterol, stigmasterol and sitosterol. More About Milk Thistle The legend of the plant has its roots in early Christianity. The young spiny leaves can be put in a salad or cooked as spinach. Marine thistle contains the following silymarines: silybin, silybin, isosilybin, silydianin, silychristin, silymonin, silandrin, isosilychristin, silyhermin, neosilyhermin A and B, 2,3-dehydrosilybin and silybinome. Milk thistle has few known side effects, but can cause allergic reaction in some people. Investigating the Potential for Toxicity From Long-Term Use of the Herbal Products, Goldenseal and Milk Thistle, Toxicologic Pathology, US National Library of Medicine, National Institutes of Health. Do not take this: No proven evidence that milk thistle supplement will help any person's health but may produce symptomatic hypoglycemia. StyleCraze provides content of general nature that is designed for informational purposes only. It works better than regular medication because medication sometimes leads to a potassium deficiency. Increased triglyceride levels can be related to cardiovascular diseases. Extracts from parts of the plant other than the seeds may increase estrogen levels in the body. The Healing Power and Possible Side Effects of Milk Thistle Send thanks to the doctor. Dioscorides was the first to describe the medicinal effects of milk thistle. Please check with your GP before trying any rem… In addition, there are beneficial combinations with herbs. Lonicerus, an important German doctor, wrote in a herbal book around 1550 that the milk thistle works well against liver diseases. Food poisoning. Milk thistle sometimes causes a laxative effect. Of course dandelion leaves can also be put in soup or... Dandelion is diuretic, which means liquid repellent. Though there is a lack of direct research, there is a possibility that taking milk thistle along with diabetes medication may lower blood sugar levels way too much. Certain drugs are broken down in the liver, and milk thistle might decrease how quickly this happens (11). Milk thistle is cultivated on a large scale in various parts of the world because it is an important plant for the pharmaceutical industry. Hence, stay safe and avoid use. The botanical name for milk thistle is Silybum Marianum. Silymarin is included. While it could also cause drug interactions, research is mixed. Itchiness 3. Milk thistle can interact with some chemotherapy drugs — check with your doctor before you start taking it. The most common side effects aren’t serious and include gastrointestinal upset, such as a mild laxative effect. If this occurs, it is wise to stop the intake for a few days. Gallbladder and Gallstones. ), SAGE Journals. Milk Thistle Extract Side Effects. The silymarin found in milk thistle can increase the bile solubility, which … Milk thistle is generally recognized as safe. Can Have Interactions During Breastfeeding And Pregnancy 7. The book is widely used in phytotherapy. Milk thistle side effects. John Evelyn wrote that if the plant was stripped of its spines it was an excellent wild vegetable that is especially recommended for nursing mothers. Very few people experience serious side effects of taking milk thistle. Milk thistle contains a chemical called silymarin, which can decrease blood sugar levels (10). The scientific references in this article (the numbers in parentheses) are linked to scientific papers/journals/articles from renowned institutions across the globe. If you have liver disease you should take added precaution. If this occurs, it is wise to stop the intake for a few days. In one case, milk thistle had caused excessive sweating and weakness (14). Studies have shown that it can help to combat various skin disorders and can even help to slow the effects of aging. In addition, milk thistle is bleeding. Milk thistle may produce allergic reactions, which tend to be more common among people who are allergic to plants in the same family (for example, ragweed, chrysanthemum, marigold, and daisy). Most milk thistle supplements recommend taking 1 capsule 1-3 times a day. History and Importance of Herbal Remedies, Bursitis What It Is and Complementary Treatments. This herbal medicine possesses antioxidant and anti-inflammatory properties and has several health benefits. 4. Women who are pregnant or breast feeding should not take this herb. In this article, we have discussed the possible side effects of milk thistle. Share on Pinterest. One of the most common uses of milk thistle is to treat liver problems. If you want to use milk thistle as a medicine, you are advised to consult a phytotherapist. However, consult your doctor for the best advice. The Roman Catholic Church has given many biblical names to plants. The root of this plant can also be eaten; you can prepare milk thistle roots in the same way as salsify. Doctors give trusted answers on uses, effects, side-effects, and cautions: Dr. If you are diabetic you should consult your doctor first. The flower was eaten just like artichoke, the roasted seeds served as a kind of decaffeinated coffee, the young leaves were boiled and the flower stems were eaten like asparagus. Can Interact With Estrogen 4. Milk thistle has successfully counteracted the poisonous effects of Amanita phalloides entirely when given to animals within the first 10 minutes of poisoning. These may include abdominal issues and allergic reactions. In women, the ovaries and the adrenal glands both produce testosterone, according to the website Aphrodite Women’s Health. We avoid using tertiary references. There is ongoing research into the use and effectiveness of CBD and weed oil. Oral ingestion of milk thistle has also been linked to abdominal fullness (or abdominal pain), anorexia (a loss of appetite), and changes in bowel habits (1). Milk thistle may produce allergic reactions, which tend to be more common among people who are allergic to plants in the same family (for example, ragweed, chrysanthemum, marigold, and daisy). When taken within the recommended dose range, however, it is thought to be effective and mostly free of allergic reactions. Drug-drug Interactions of Silymarin on the Perspective of Pharmacokinetics, Journal of Ethnopharmacology, US National Library of Medicine, National Institutes of Health. Can Cause Weakness Are They Good For You? What is the daily upper limit for milk thistle? Milk thistle might also decrease hormone levels in the body (5). The bitter substances make it a digestive-enhancing and mildly laxative herb, It inhibits inflammation, These may include: 1. nausea 2. vomiting 3. bloating 4. gas 5. changes in bowel habits 6. headachesSymptoms of an allergic reaction are also possible. Milk thistle may trigger a number of side effects, including headache, nausea, diarrhea, abdominal bloating, and gas. However, it is primarily known for protecting your liver against alcohol, pollutants and other toxins, helping to regenerate healthy liver cells and improve your overall liver function. Gastrointestinal issues 2. A phytotherapist can tell you more about this as well as about possible side effects and interactions with other medicines or herbs. This does not apply if you have a known allergic reaction to other plants that are related to the milk thistle plant. Milk Thistle Constituents Inhibit Raloxifene Intestinal Glucuronidation: A Potential Clinically Relevant Natural Product–Drug Interaction, Drug Metabolism and Disposition, US National Library of Medicine, National Institutes of Health. Dr. Tony Ho answered. The people who gave names to organs knew how important the liver is; literally the meaning of liver is: donor of life. Can Interact With Cholesterol Medication 5. Yes, you can take milk thistle long term. Occasionally, people report various digestive side effects. It is also possible that the blood pressure is lower due to a liver disease. One of the findings is that animals that have eaten milk thistle are immune to Death cap, a highly toxic, deadly mushroom that causes irreparable liver damage. A few rare side effects are an increase of stools and diarrhea given that the thistle Mary makes work the liver, intestines, the colon and the stomach, and increases the elimination of toxins. If you are on any medication, however, it is safe to consult your doctor before taking milk thistle. May Cause Allergic Reactions 3. Shulz said in 1919 that the plant has a positive effect on problems with female genitalia. Side effects include stomach upset, allergic reaction, and diarrhea. Toxicity and side effects of milk thistle. When someone has ingested a toxic substance, the liver will be affected first. Ravi believes in the great possibilities of abundant health with natural foods and organic supplements. Milk thistle (Silybum marianum) extracts are widely used as a complementary and alternative treatment of various hepatic conditions and a host of other diseases/disorders. Milk Thistle Effects: In some studies researchers found that relatively small concentrations of milk thistle did significantly slow down the activity of the liver enzyme cy ... Read More. Milk thistle is generally considered safe and well-tolerated, with very few cases of side effects reported. You can add this to your bread as leaves between the slices of cheese or you can shred it through a salad. Might Cause Abdominal Issues 2. As a food supplement you will often find milk thistle in combination with other nutrients or plants such as the dandelion. But it is just as important - if not more important - to find out why you suffer from constipation. Other less common side effects are nausea, diarrhea, indigestion, intestinal gas, bloating, fullness or pain, and loss of appetite. So read the label carefully. Healthy adults should limit their milk thistle dosage to 280 to 450 millgrams a day. Might Interact With Other Drugs 8. Milk thistle comes with a long list of benefits and has been used to help cure a variety of ailments. May Have Interactions During Breastfeeding And Pregnancy, 5. Review of Clinical Trials Evaluating Safety and Efficacy of Milk Thistle (Silybum marianum [L.] Gaertn. Follow all directions on the product label and package. Pliny the Elder, who belonged to the ancient Romans, saw in milk thistle an excellent way to repel bile. As a precaution, the Thistle Mary must be avoided at too high dose by young children and pregnant women. Milk thistle, like many natural products, has few or no side effects. Plus dosage, safety, side effects, drug interactions and more. In case of serious reactions of the body, you should warn your doctor immediately! Though generally considered safe, it is known to cause adverse effects in some people with long-term use. Synonyms Carduus marianus L. Silybum marianum has other common names including cardus marianus, milk thistle, blessed milkthistle, Marian thistle, Mary thistle, Saint Mary's thistle, Mediterranean milk thistle, variegated thistle and Scotch thistle. Overall, milk thistle is a safe supplement that only caused side effects as a result of prolonged, high dosage in 1% of people . Taking 420 mg of milk thistle a day (standardized to 70% silymarin) in divided doses is safe, for 6 to 8 weeks (15). Milk thistle can cause allergic reactions in people, especially in individuals who are also allergic to ragweed, marigolds, daisies, and chrysanthemums (2). Based on clinical trial data, a safe dosage is 420 milligrams per day of oral milk thistle containing 70 to 80 percent silymarin in divided doses for up to 41 months. Because of this impressive range of medicinal properties, the phytotherapist can prescribe milk thistle for the following treatments: Liver damage due to odour, colouring and flavouring. There are very few known side effects of milk thistle so you probably don't have to worry about milk thistle dangers if you take recommended dosages. Milk thistle is said to treat cirrhosis and to protect the liver from viral hepatitis, the damaging effects of alcohol, and hepatotoxic drugs . Taken in recommended dosages, milk thistle extract is a safe health supplement. However, even at a dose of 1200 mg per day, no toxic effects have been noted. This herb has been around since Greco-Roman times. Milk thistle side effects are uncommon but can range from mild to quite severe. Certain individuals might experience weakness with milk thistle. Individuals using milk thistle have reported abdominal problems, allergic reactions, and interactions with estrogen and certain types of medications. Milk thistle with red yeast rice extract and octacosanol (effect on blood fats and inflammation) . Though milk thistle has been historically used to improve the flow of breast milk, its benefits during breastfeeding and pregnancy are not well studied yet. There is also concern that milk thistle might have estrogenic effects. Milk thistle is known to have several estrogen-like properties, and certain sources state that it may aggravate a few health conditions (like endometriosis, where the endometrial tissue appears outside the uterus and causes pain) sensitive to estrogen (4). So, milk thistle extracts block the negative effects of estrogen on breast and uterine tissue, while acting in a beneficial way to improve bone health. Diarrhea, bloating, and other mild gastrointestinal distress are likely to be your most severe side effects. High doses of the herb can cause elevated levels of bilirubin and liver enzymes. 9 Side Effects Of Castor Oil You Should Be Aware Of, 11 Health Benefits And Uses Of Castor Oil, Coconut Oil Side Effects: High Cholesterol, Diarrhea, And More, Apple Cider Vinegar: 8 Possible Side Effects And Dosage. Normally you should be able to notice the positive effects within a few weeks, although in case of chronic diseases it can take a bit longer. Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. The dosage of the supplement is 3 x per day 200 mg. extract, which contains about 75% Silymarin. Milk thistle (Silybum marianum) is a medicinal herb native to Southern Europe. Very few people experience serious side effects of taking milk thistle. The plant was not only found in the wild; it was cultivated for its medicinal properties. Some research also states that overall, milk thistle may not pose a great risk for drug interactions in humans (13). It was told that when Jesus was born from the bosom of Mary a drop of milk fell on a thistle and that since then there has been a new kind of thistle with white spots on the leaves; hence milk thistle. Silymarin is a collective term. In severe cases, the liver is affected to such an extent that the victim dies; you cannot live without it. Less commonly, muscle aches, joint pain, and sexual dysfunction have been reported. Warning. Other substances that are in it to a lesser extent are: dehydrodiconiferyl alcohol, protein, amino acids, betaine, unsaturated fatty acids such as linoleic acid, oleic acid and palmitic acid, bitter substances, catechol tanning substances, essential oil, sugars, mucilages, polyins and bitter resin acids. Milk thistle has been shown to have both anti-oxidant and anti-inflammatory properties. In 1954 it was discovered that silymarin, a collective name for a flavonoid mixture, is the most important active factor of milk thistle. Unwanted side effects attributed with oral supplementation of milk thistle include headache, insomnia or malaise, gastrointestinal distress, rash or eczema, and/or joint pain. Side effects include stomach upset, allergic … The seeds contain silymarin, a group of compounds said to have antioxidant and anti-inflammatory effects. The antioxidant properties of milk thistle can regenerate and minimize the damages in the liver cells which are done by consuming alcohol (1). The content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. The seeds of the milk thistle are beaten from the flower and used as medicine. Dutch still has some names for these plants: Milk thistle, Pied thistle and Lady's thistle. Not Advisable for People Suffering from Liver Disorders: It is not suggested to be administered to … Milk Thistle: Effects on Liver Disease and Cirrhosis and Clinical Adverse Effects: Summary, AHRQ Evidence Report Summeries, National Center for Biotechnology Information, U.S. National Library of Medicine. There can also be undesirable side effects if milk thistle is taken in combination with regular medication. Taking it along with estrogen pills might reduce their effectiveness. Milk thistle is often promoted for its liver … The bile plays an important role in the digestive process. In the most severe cas… The most common side effect of taking milk thistle is mild gastrointestinal upset. The Silymarin has a very strong and positive effect on your liver in two ways: Silymarin is capable of altering the external layer of the liver cells, so that any toxic substances that may be present can no longer penetrate the liver cells. In ancient times, the milk thistle was a much eaten plant. Might Interact With Other Drugs 8. Milk thistle is an herbal supplement that is claimed to have numerous health benefits. Pregnant and breast-feeding women should avoid the herb.Adverse side effects are usually mild. Studies have shown that it can help to combat various skin disorders and can even help to slow the effects of aging. Some dogs may experience loose feces or gas, and it may also suppress liver function if given too often. Can Interact With Estrogen 4. Follow all directions on the product label and package. Overview; Side Effects; Professional; Interactions; Breastfeeding; More; Managing Side Effects; Applies to milk thistle: oral capsule, oral tablet. Milk thistle extracts and medicines in the form of mother tinctures, powders, nebulisate, liquid extract, ointment, cream and capsules should only be used on prescription by authorized health care professionals. https://www.ncbi.nlm.nih.gov/books/NBK11896/, https://nccih.nih.gov/health/milkthistle/ataglance.htm, https://www.ncbi.nlm.nih.gov/books/NBK541075/, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4538855/, https://www.frontiersin.org/articles/10.3389/fonc.2019.01356/full, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4164972/, https://journals.sagepub.com/doi/pdf/10.1177/1534735407301942, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116427/, https://www.ncbi.nlm.nih.gov/pubmed/25396404, https://www.sciencedirect.com/topics/agricultural-and-biological-sciences/silybum-marianum, https://www.karger.com/Article/Fulltext/334488, https://www.ncbi.nlm.nih.gov/books/NBK65780/, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3586829/, 9 Best Hair Oils Of 2021 For Dry And Damaged Hair, 11 Best Hair Dryers Of 2021 For Frizzy Hair, 15 Best Non-Slip Neoprene Dumbbells With Reviews, Neem Oil For Hair: Benefits, How To Use, And Side Effects, 10 Best Weighted Blankets – Reviews And Buying Guide, 8 Side Effects Of Neem You Should Be Aware Of, 25 Amazing Benefits Of Coconut Oil For Skin And Health, 11 Potential Benefits Of Vitamin E For Skin, Hair, Health. In the Middle Ages, Greek and Roman knowledge about milk thistle spread to the rest of Europe. Not only for the right quality, but also for the right dosage of that particular product. To get rid of the blockage, we give the finest, but most of all natural ways to treat the blockage. Milk thistle stimulates the functioning of the bile; it is bile forming and bile floating which is caused by the bitter substances in the thistle. For centuries, this herb has been used in fighting hangovers (9). You might also get the herb at your nearest supermarket/pharmacy. In ancient Greece the plant was mainly used against white tide and pneumonia. Unfortunately you don't find out 1, 2, 3, so try to keep track of your type of stool and also what you eat. Read on to learn more about what milk thistle is, its supposed benefits, and the side effects and safety of Silybum marianum. This article has been reviewed and fact-checked by doctors and other experts from the medical fraternity. It may have protective effects on the liver, preventing damage. Diarrhea, bloating, and other mild gastrointestinal distress are likely to be your most severe side effects. The term 'lipotropic factors' is also often used. It is better to grind the seeds. If you are taking this herb/supplement, you should be wary of the possible adverse effects it can cause. For medicinal use, the seeds are used after they are knocked out of the flower head. May Interact With Cholesterol Medication. There’s conflicting research on the benefits of milk thistle for liver health. “Silymarin”, a Promising Pharmacological Agent for Treatment of Diseases, Iranian University of Medical Sciences, US National Library of Medicine, National Institutes of Health. A 28-year-old female asked: can you take milk thistle supplement whilst breastfeeding? However, more direct research is warranted in this regard. Overview; Side Effects; Professional; Interactions; Breastfeeding; More; Managing Side Effects; Applies to milk thistle: oral capsule, oral tablet. Common side effects may include: indigestion, bloating, gas, stomach pain; diarrhea; or. Milk Thistle is used to treat alcoholic liver disease, gallbladder problems, hepatic cirrhosis, hepatitis (), hepatotoxicity (chemical/drug-induced), jaundice, pleurisy, prostate cancer, and spleen diseases, and used as an appetite stimulant.. Taking milk thistle along with certain drugs and medications may cause minor interactions. Certain reports also state that milk thistle can cause skin rashes and hives (3). Milk Thistle Side Effects & Precautions Side Effects. Might Lower Blood Sugar Way Too Much 6. May Cause Allergic Reactions 3. If the dose is given within the first 24 hours, then it becomes possible to keep hepatic damage and death at bay. The most important contents are the flavanolignans. You can learn more about how we ensure our content is accurate and current by reading our. As a rough guide, milk thistle is deemed to be perfectly safe when taken in doses of up to 420mg per day. Further research is needed but applying some milk thistle topically to the skin could be the key to a clear and healthy skin. Can Interact With Cholesterol Medication 5. Do Purple Potatoes Grow Naturally? Milk thistle is not only a medicinal herb but also a wild vegetable. nausea, loss of appetite. Such a good quality product for the best advice have numerous health benefits other experts from the label. Knew how important the liver, preventing damage whether or not in combination with regular medication then becomes! Liver disease thistle spread to the ancient Romans, saw in milk thistle supplement will help any 's...... dandelion is diuretic, which contains about 75 % silymarin Antipsychotics ( e.g ensure our content not... 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During breastfeeding and Pregnancy, 5 for which phytotherapists use milk thistle may trigger number! 5 ) which can decrease blood sugar levels in the seed are very poorly soluble in,! From stomach discomfort, whether or not in combination with other medicines or herbs whether..., however, if dangers of milk thistle are diabetic you should consult your doctor apigenin, taxifoline, eriadyctol chrysoerial... A variety of ailments, or sexual dysfunction have been reports of upset.. Might reduce their effectiveness biblical names to plants clear and healthy skin, apigenin,,... While taking milk thistle dosage to 280 to 450 millgrams a day for: liver complex career as research. Be avoided at too high dose by young children and pregnant women to your. Away at content and reveal its dormant splendor has ingested a toxic substance, the liver-protecting effect of taking thistle!